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Portfolio Holdings Detail for ISIN IE00BYZK4776
Stock Name / FundiShares Healthcare Innovation UCITS ETF USD (Acc)
IssuerBlackrock
Entity holding fund iShares IV Public Limited Company
Entity TypeUmbrella investment company with variable capital and having segregated liability between its funds
Entity LEI 549300ZP07LMR36K1T02
ETF TickerDRDR(GBX) LSE
ETF Ticker2B78(EUR) F
ETF Ticker2B78.DE(EUR) CXE
ETF TickerDRDR.LS(GBX) CXE
ETF TickerHEAL.AS(EUR) CXE
ETF TickerHEAL.LS(USD) CXE
ETF TickerHEALz(USD) CXE
ETF TickerHEAL(EUR) ETF Plus
ETF TickerDRDR.L(GBP) LSE

Holdings detail for IONS

Stock NameIonis Pharmaceuticals Inc
TickerIONS(USD) NASDAQ
TYPECommon Stock
CountryUSA
ISINUS4622221004
LEI549300SI4ZGLG0BLUZ92

Show aggregate IONS holdings

News associated with IONS

Ionis Pharma Reports Positive Topline Results From Pivotal Study Of Zilganersen In Alexander Disease
(RTTNews) - Ionis Pharmaceuticals, Inc. (IONS) announced Monday positive topline results from the pivotal study of zilganersen in children and adults living with Alexander disease (AxD), a rare, progressive and often fatal neurological condition with no approved disease-modifying - 2025-09-22 08:36:13
Ionis Pharmaceuticals And Sobi Say EU Approves TRYNGOLZA For Familial Chylomicronemia Syndrome
(RTTNews) - Ionis Pharmaceuticals, Inc. (IONS) and Swedish biopharmaceutical company Sobi announced Friday that TRYNGOLZA (olezarsen) has been approved in the European Union (EU) as an adjunct to diet in adult patients for the treatment of genetically confirmed familial chylomicr - 2025-09-19 08:39:56
7 Biotech Stocks Trading At 52-Week Highs - Can The Rally Continue?
(RTTNews) - Patience is a virtue - important in all aspects of life, and especially crucial when it comes to investing. As trading expert Steve Burns once said, "Much of our trading comes down to a battle between our patience and our impulses." - 2025-09-15 03:55:16
Citigroup Increases Ionis Pharmaceuticals (NASDAQ:IONS) Price Target to $84.00
Ionis Pharmaceuticals (NASDAQ:IONS – Get Free Report) had its target price boosted by equities research analysts at Citigroup from $69.00 to $84.00 in a report released on Wednesday,Benzinga reports. The firm currently has a “buy” rating on the stock. Citigroup’s price target points to a potential upside of 41.53% from the stock’s previous close. A […] - 2025-09-05 05:03:17
IONS Crosses Above Average Analyst Target
In recent trading, shares of Ionis Pharmaceuticals Inc (Symbol: IONS) have crossed above the average analyst 12-month target price of $59.91, changing hands for $60.49/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgra - 2025-09-04 08:06:06
Ionis Pharmaceuticals (NASDAQ:IONS) Stock Price Expected to Rise, HC Wainwright Analyst Says
Ionis Pharmaceuticals (NASDAQ:IONS – Get Free Report) had its price target hoisted by investment analysts at HC Wainwright from $70.00 to $95.00 in a research note issued on Tuesday, MarketBeat Ratings reports. The brokerage presently has a “buy” rating on the stock. HC Wainwright’s price target points to a potential upside of 57.05% from the […] - 2025-09-04 04:34:50
Ionis Pharmaceuticals (NASDAQ:IONS) Sees Strong Trading Volume on Analyst Upgrade
Shares of Ionis Pharmaceuticals, Inc. (NASDAQ:IONS – Get Free Report) saw strong trading volume on Wednesday after Citigroup raised their price target on the stock from $69.00 to $84.00. Citigroup currently has a buy rating on the stock. 1,757,603 shares changed hands during trading, a decline of 5% from the previous session’s volume of 1,844,968 […] - 2025-09-04 02:20:48
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 14:33:33
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 13:44:52
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 12:52:53
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 12:27:04
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 10:14:11
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 08:10:07
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 06:59:07
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 05:15:06
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 04:43:16
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 03:40:04
Stocks Retreat as Bond Yields Climb
The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 01:21:35
Stocks Tumble on Higher Bond Yields
The S&P 500 Index ($SPX ) (SPY ) today is down by -1.26%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -1.23%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.38%. September E-mini S&P futures (ESU25 ) are down -1.25%, and September... - 2025-09-02 20:15:06
Stocks Under Pressure from Higher Bond Yields
The S&P 500 Index ($SPX ) (SPY ) today is down by -1.15%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -0.83%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.32%. September E-mini S&P futures (ESU25 ) are down -1.15%, and September... - 2025-09-02 17:45:25
Stocks Under Pressure from Higher Bond Yields
The S&P 500 Index ($SPX ) (SPY ) today is down by -1.15%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -0.83%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.32%. September E-mini S&P futures (ESU25 ) are down -1.15%, and September... - 2025-09-02 13:49:14
Stocks Tumble on Higher Bond Yields
The S&P 500 Index ($SPX ) (SPY ) today is down by -1.26%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -1.23%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.38%. September E-mini S&P futures (ESU25 ) are down -1.25%, and September... - 2025-09-02 13:32:33
Stocks Tumble on Higher Bond Yields
The S&P 500 Index ($SPX ) (SPY ) today is down by -1.26%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -1.23%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.38%. September E-mini S&P futures (ESU25 ) are down -1.25%, and September... - 2025-09-02 12:50:37
Stock Traders Buy High Volume of Call Options on Ionis Pharmaceuticals (NASDAQ:IONS)
Ionis Pharmaceuticals, Inc. (NASDAQ:IONS – Get Free Report) was the recipient of unusually large options trading activity on Wednesday. Stock traders bought 2,862 call options on the stock. Thisisanincreaseofapproximately218% compared to the average volume of 899 call options. Ionis Pharmaceuticals Stock Down 0.3% Shares of IONS opened at $42.62 on Friday. The firm has a […] - 2025-08-29 02:34:43
Ionis Pharmaceuticals (NASDAQ:IONS) Price Target Raised to $49.00 at JPMorgan Chase & Co.
Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price target boosted by JPMorgan Chase & Co. from $48.00 to $49.00 in a research report report published on Monday morning,Benzinga reports. They currently have a neutral rating on the stock. A number of other equities research analysts also recently weighed in on the stock. Needham & […] - 2025-08-26 03:10:58
Citigroup Increases Ionis Pharmaceuticals (NASDAQ:IONS) Price Target to $69.00
Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price objective upped by Citigroup from $65.00 to $69.00 in a report released on Friday morning,Benzinga reports. Citigroup currently has a buy rating on the stock. A number of other equities analysts also recently commented on IONS. HC Wainwright raised their price objective on Ionis Pharmaceuticals from […] - 2025-08-25 05:00:49
Barclays Forecasts Strong Price Appreciation for Ionis Pharmaceuticals (NASDAQ:IONS) Stock
Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price objective upped by Barclays from $57.00 to $58.00 in a research report report published on Friday morning,Benzinga reports. They currently have an overweight rating on the stock. Several other research firms have also recently weighed in on IONS. JPMorgan Chase & Co. increased their price target […] - 2025-08-25 02:58:58
HC Wainwright Raises Ionis Pharmaceuticals (NASDAQ:IONS) Price Target to $70.00
Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price objective lifted by HC Wainwright from $65.00 to $70.00 in a report released on Friday morning,Benzinga reports. They currently have a buy rating on the stock. Other analysts also recently issued research reports about the stock. Guggenheim reduced their price target on shares of Ionis Pharmaceuticals […] - 2025-08-25 02:58:55
Ionis Pharmaceuticals (NASDAQ:IONS) Stock Rating Upgraded by Wall Street Zen
Ionis Pharmaceuticals (NASDAQ:IONS – Get Free Report) was upgraded by research analysts at Wall Street Zen from a “hold” rating to a “buy” rating in a research report issued to clients and investors on Saturday. A number of other analysts have also issued reports on IONS. Barclays raised Ionis Pharmaceuticals from an “equal weight” rating […] - 2025-08-18 04:37:05
Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Shares Sold by Swiss National Bank
Swiss National Bank decreased its stake in Ionis Pharmaceuticals, Inc. (NASDAQ:IONS – Free Report) by 1.4% in the 1st quarter, according to the company in its most recent filing with the Securities and Exchange Commission. The institutional investor owned 275,300 shares of the company’s stock after selling 3,900 shares during the period. Swiss National Bank’s […] - 2025-08-17 05:21:00

iShares Healthcare Innovation UCITS ETF USD (Acc) IONS holdings

DateNumber of IONS Shares HeldBase Market Value of IONS SharesLocal Market Value of IONS SharesChange in IONS Shares HeldChange in IONS Base ValueCurrent Price per IONS Share HeldPrevious Price per IONS Share Held
Share price and value of shares held is calculated on the adjusted close price of each day (row). Changes between days reflect the gain/loss of the portfolio as a result of changes in the adjusted close price and changes in the holdings

Share Trades of IONS by Blackrock for IE00BYZK4776

Show aggregate share trades of IONS

DateActionQuantityMarket HighMarket LowLikely Trade PriceLikely Trade Value (Profit/Loss)Average Price previous trades
2025-06-11SELL-74636.19036.980 36.901USD -27,528 33.31 Loss of -2,677 on sale
2025-05-30SELL-74733.51033.880 33.843USD -25,281 33.20 Loss of -480 on sale
2025-05-21BUY74633.50034.610 34.499USD 25,736 33.20
2025-05-14SELL-4,47632.60033.200 33.140USD -148,335 33.19 Profit of 230 on sale
2025-04-30SELL-74630.71031.820 31.709USD -23,655 33.25 Profit of 1,152 on sale
2025-04-28SELL-74629.74030.090 30.055USD -22,421 33.32 Profit of 2,432 on sale
2025-04-25SELL-74629.70029.900 29.880USD -22,290 33.35 Profit of 2,587 on sale
2025-04-11SELL-4,49427.90027.970 27.963USD -125,666 33.82 Profit of 26,299 on sale
2025-04-08SELL-2,24425.51028.140 27.877USD -62,556 34.03 Profit of 13,816 on sale
2025-04-07BUY2,13227.57027.610 27.606USD 58,856 34.10
2025-03-31SELL-1,46630.17030.480 30.449USD -44,638 34.35 Profit of 5,719 on sale
2025-03-21SELL-1,46632.91033.620 33.549USD -49,183 34.50 Profit of 1,395 on sale
2025-03-12SELL-73533.41034.130 34.058USD -25,033 34.61 Profit of 407 on sale
2025-02-28SELL-73533.19033.300 33.289USD -24,467 34.76 Profit of 1,084 on sale
2025-02-25BUY73531.85032.090 32.066USD 23,569 34.90
2025-02-20SELL-73532.69033.070 33.032USD -24,279 35.02 Profit of 1,459 on sale
2025-02-19BUY1,47031.81034.740 34.447USD 50,637 35.07
2025-02-18BUY73531.95032.180 32.157USD 23,635 35.12
2025-01-22SELL-73432.50032.930 32.887USD -24,139 36.27 Profit of 2,483 on sale
2025-01-17SELL-73431.43032.950 32.798USD -24,074 36.59 Profit of 2,780 on sale
2024-12-30BUY2,66734.92035.800 35.712USD 95,244 37.34
2024-12-06SELL-71638.11039.170 39.064USD -27,970 37.24 Loss of -1,305 on sale
2024-12-04SELL-71637.15037.200 37.195USD -26,632 37.26 Profit of 48 on sale
2024-12-03SELL-1,43235.81036.070 36.044USD -51,615 37.32 Profit of 1,821 on sale
2024-11-21SELL-71933.94035.650 35.479USD -25,509 38.16 Profit of 1,931 on sale
2024-11-20SELL-72435.40035.600 35.580USD -25,760 38.32 Profit of 1,982 on sale
2024-11-19SELL-72433.75034.420 34.353USD -24,872 38.59 Profit of 3,065 on sale
2024-11-18SELL-2,86833.73034.790 34.684USD -99,474 38.89 Profit of 12,063 on sale
2024-11-12SELL-71737.77038.770 38.670USD -27,726 38.96 Profit of 211 on sale
2024-11-07SELL-71738.46039.800 39.666USD -28,441 38.99 Loss of -487 on sale
2024-11-05SELL-1,43438.80039.200 39.160USD -56,155 39.00 Loss of -232 on sale
2024-10-28SELL-71740.36040.410 40.405USD -28,970 38.81 Loss of -1,142 on sale
Market high and low price is on the date.

* (if shown) = market close price used not a projected price. This is used when we do not have market data available to calculate a projection

The likely trade price/value is our estimate on the likely price the trade took place at and is not the actual trade price. The likely LOSS/GAIN is our estimate. Where a profit/loss value is shown in the Likely Trade Value column, this is derived from matching trades between periods eg the most recent previous BUY is matched with the SELL for the same number of shares and the difference between the likely BUY price and likely SELL price is calculated. Where a profit or loss is shown in the Average Price of Previous Trades column, this is dervied using the likely trade price compared to the average of previous trades based on adjusted close

Shorting History of IONS

DateShorted VolumeShort Exempt VolumeTotal Shares Traded% Shorted
2025-09-19217,7177,823943,82523.1%
2025-09-18336,1303,248634,20253.0%
2025-09-17238,8163,302589,66540.5%
2025-09-16278,3915,001657,60342.3%
2025-09-15467,4916,458854,45254.7%
2025-09-12363,5157,545614,11459.2%
2025-09-11401,18811,402693,03757.9%
2025-09-10588,94819,742863,14768.2%
2025-09-091,181,81273,0351,940,60660.9%
2025-09-08583,89616,300960,78460.8%
2025-09-05721,34759,6601,251,12357.7%
2025-09-04724,80245,1121,541,38747.0%
2025-09-032,076,447142,9914,309,70048.2%
2025-09-024,524,907272,2597,686,23658.9%
2025-08-29252,225110399,46163.1%
2025-08-28222,625238400,17955.6%
2025-08-27385,029566728,94452.8%
2025-08-26249,2242969,58825.7%
2025-08-25361,205100557,38964.8%
2025-08-22311,576404771,17140.4%
2025-08-21409,36121,497673,65960.8%
2025-08-20481,0356,774795,97860.4%
2025-08-19541,80681,496869,01062.3%
2025-08-18256,88812,986522,50149.2%
2025-08-15213,408327507,64942.0%
2025-08-14333,49610,831740,98945.0%
2025-08-13638,5211,3201,526,41641.8%
2025-08-12135,834604616,87022.0%
2025-08-11179,9501,191536,29333.6%
2025-08-08130,7070509,71925.6%
2025-08-07181,35141,011,17417.9%
2025-08-06367,35222954,39438.5%
2025-08-05227,7131,636729,72931.2%
2025-08-04264,6993,930961,83727.5%
2025-08-01391,5983,0271,051,32237.2%
2025-07-31956,60110,4351,943,11549.2%
2025-07-30565,33221,544,80636.6%
2025-07-29155,3300519,33529.9%
2025-07-28192,3932,369530,08336.3%
2025-07-25146,3911,318319,26145.9%
2025-07-24115,623124259,04444.6%
2025-07-23345,7620687,48750.3%
2025-07-22180,2310525,15834.3%
2025-07-21354,6920590,19160.1%
2025-07-18194,72746499,18139.0%

The data here is derived from FINRA daily shorted trade data. The Daily Short Sale Volume is the total volume of short trades that meet certain criteria on each trade date by 6 PM ET on the trade date. The detail trade data is derived from the monthly shorted trade data which will differ in aggregate. The detail trade data is derived from the transaction level data and includes ALL trades (including exempt) and the aggregation period extends beyond 6pm.

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Note: All information is provided as is without warranty and should be used for indicative purposes only. You should independently check data before making any investment decision. This information is derived from third party sources and we cannot guarantee that their data is current, accurate, complete, free from defects etc and we therefore accept no responsibility for how it may be used. We accept no liability.

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